ABIN1450096

antibody from antibodies-online

Targeting: AFAP1 AFAP, AFAP-110

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN1450096

Provider

antibodies-online

Product name

anti-Actin Filament Associated Protein 1 (AFAP1) (N-Term) antibody

Antibody type

Polyclonal

Antigen

Other

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

References

Submitted references

AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts.

Zhang J, Park SI, Artime MC, Summy JM, Shah AN, Bomser JA, Dorfleutner A, Flynn DC, Gallick GE
The Journal of clinical investigation 2007 Oct;117(10):2962-73

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The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases.

Baisden JM, Gatesman AS, Cherezova L, Jiang BH, Flynn DC
Oncogene 2001 Oct 4;20(45):6607-16

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The actin filament-associated protein AFAP-110 is an adaptor protein that modulates changes in actin filament integrity.

Baisden JM, Qian Y, Zot HM, Flynn DC
Oncogene 2001 Oct 1;20(44):6435-47

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Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate.

Flynn DC, Leu TH, Reynolds AB, Parsons JT
Molecular and cellular biology 1993 Dec;13(12):7892-900

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of AFAP1 in Hela cell lysate with AFAP1 antibody Cat.-No AP55595PU-N at (A) 1 and (B) 2 ug/ml.