Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15617-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15617-1-AP, RRID:AB_2169527
- Product name
- PRC1 antibody
- Antibody type
- Polyclonal
- Description
- PRC1 antibody (Cat. #15617-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identifying and Validating Potential Biomarkers of Early Stage Lung Adenocarcinoma Diagnosis and Prognosis.
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer.
Aurora kinase B inhibits aurora kinase A to control maternal mRNA translation in mouse oocytes.
PRC1 is a critical regulator for anaphase spindle midzone assembly and cytokinesis in mouse oocyte meiosis.
Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse.
Piperlongumine promotes death of retinoblastoma cancer cells.
Cdk1 negatively regulates the spindle localization of Prc1 in mouse oocytes.
Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice.
Chen Y, Jin L, Jiang Z, Liu S, Feng W
Frontiers in oncology 2021;11:644426
Frontiers in oncology 2021;11:644426
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer.
Li J, Ohmura S, Marchetto A, Orth MF, Imle R, Dallmayer M, Musa J, Knott MML, Hölting TLB, Stein S, Funk CM, Sastre A, Alonso J, Bestvater F, Kasan M, Romero-Pérez L, Hartmann W, Ranft A, Banito A, Dirksen U, Kirchner T, Cidre-Aranaz F, Grünewald TGP
Nature communications 2021 Sep 16;12(1):5356
Nature communications 2021 Sep 16;12(1):5356
Aurora kinase B inhibits aurora kinase A to control maternal mRNA translation in mouse oocytes.
Aboelenain M, Schindler K
Development (Cambridge, England) 2021 Nov 1;148(21)
Development (Cambridge, England) 2021 Nov 1;148(21)
PRC1 is a critical regulator for anaphase spindle midzone assembly and cytokinesis in mouse oocyte meiosis.
Li XH, Ju JQ, Pan ZN, Wang HH, Wan X, Pan MH, Xu Y, Sun MH, Sun SC
The FEBS journal 2021 May;288(9):3055-3067
The FEBS journal 2021 May;288(9):3055-3067
Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse.
Mihajlović AI, Haverfield J, FitzHarris G
Developmental cell 2021 Aug 23;56(16):2273-2283.e3
Developmental cell 2021 Aug 23;56(16):2273-2283.e3
Piperlongumine promotes death of retinoblastoma cancer cells.
Allaman-Pillet N, Schorderet DF
Oncotarget 2021 Apr 27;12(9):907-916
Oncotarget 2021 Apr 27;12(9):907-916
Cdk1 negatively regulates the spindle localization of Prc1 in mouse oocytes.
Nishiyama S, Yoshida S, Kitajima TS
Genes to cells : devoted to molecular & cellular mechanisms 2020 Oct;25(10):685-694
Genes to cells : devoted to molecular & cellular mechanisms 2020 Oct;25(10):685-694
Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.
Heath CM, Wignall SM
Molecular biology of the cell 2019 Jul 1;30(14):1691-1704
Molecular biology of the cell 2019 Jul 1;30(14):1691-1704
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice.
Guo J, Zhang T, Guo Y, Sun T, Li H, Zhang X, Yin H, Cao G, Yin Y, Wang H, Shi L, Guo X, Sha J, Eppig JJ, Su YQ
Proceedings of the National Academy of Sciences of the United States of America 2018 Jun 5;115(23):E5326-E5333
Proceedings of the National Academy of Sciences of the United States of America 2018 Jun 5;115(23):E5326-E5333
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 15617-1-AP(PRC1 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15617-1-AP(PRC1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRC1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PRC1. This antibody recognizes human, mouse, rat antigen. The PRC1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.