VPS52

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Description

VPS52 subunit of GARP complex

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (33250272 - 33272047)

Ensembl ID

ENSG00000223501  (ver. 103.38)

Orthologs

Mouse Vps52: ENSMUSG00000024319

UniProt

Q8N1B4

neXtProt

NX_Q8N1B4

Human splice variants
Mouse splice variants

Protein structure