ABIN500567

antibody from antibodies-online

Targeting: UIMC1 RAP80

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN500567

Provider

antibodies-online

Product name

anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

RAP80 antibody was raised against a 17 amino acid peptide from near the carboxyterminus of human RAP80.

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Storage

Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.

References

Submitted references

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.

Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP, Elledge SJ
Science (New York, N.Y.) 2007 May 25;316(5828):1194-8

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CCDC98 targets BRCA1 to DNA damage sites.

Liu Z, Wu J, Yu X
Nature structural & molecular biology 2007 Aug;14(8):716-20

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CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response.

Kim H, Huang J, Chen J
Nature structural & molecular biology 2007 Aug;14(8):710-5

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RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor.

Yan Z, Kim YS, Jetten AM
The Journal of biological chemistry 2002 Aug 30;277(35):32379-88

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of RAP80 in 293 cell lysate in (A) the absence and (B) presence of blocking peptide with AP30706PU-N at 2 ?g/ml.

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunohistochemistry of RAP80 in human spleen tissue with AP30706PU-N at 2.5 ?g/ml.