Antibody data

Product number
NBP2-47745-0.1mg - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Cadherin-16 Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Reactivity
Human, Mouse, Rat, Canine, Rabbit
Host
Mouse
Isotype
IgG
Vial size
0.1 mg
Concentration
1.0 mg/ml
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
CDH16 protein structure - NBP2-47745-0.1mg shown in red.