APR01975G

antibody from Leading Biology
Targeting: MAS1
Provider product page for APR01975G
Immunohistochemistry

Antibody data

Product number
APR01975G - Provider product page
Provider
Leading Biology
Product name
MAS1 / MAS Antibody (Extracellular Domain)
Antibody type
Polyclonal
Description
Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Reactivity
Human
Host
Rabbit
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
MAS1 protein structure - APR01975G shown in red.