Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- CABT-B9306 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human RPTPÉÇ monoclonal antibody, clone 23/SQUQc
- Antibody type
- Monoclonal
- Description
- Receptor-type protein-tyrosine phosphatase ÉÇ (RPTPÉÇ or PTPĀø) is the first mammalian tyrosine phosphatase to be characterized whose expression is limited to the nervous system. RPTPÉÇ consists of a large extracellular domain, a single transmembrane domain, and a cytoplasmic portion with two tandem catalytic domains. Three forms of RPTPÉÇ exist which appear to be derived from alternative splicing. The 9.5 kb and 6.4 kb transcripts encode two transmembrane forms. The 8.5 kb transcript encodes a secreted form of the extracellular domain of RPTPÉÇ. A region of 266 amino acids in the extracellular domain shows a high degree of homology with carbonic anhydrase. This region is very similar to rat brain chondroitin sulfate proteoglycan (3F8 PG) which appears to be the rat homologue of the entire extracellular domain of human RPTPÉÇ. The apparent molecular weight of human RPTPÉÇ is 250 kDa and approaches 300 kDa when the protein is glycosylated. This antibody was generated against a region known to have a high degree of homology to other proteoglycans, such as RPTPÎÛ (75% homology).
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 23/SQUQc
- Vial size
- 50ug, 150ug
- Concentration
- 250 Ã×g/ml
- Storage
- Store undiluted at -20°C.
No comments: Submit comment
No validations: Submit validation data