FNab00078

antibody from FineTest Biotech

Targeting: ACD Pip1, Ptop, Tint1, Tpp1

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab00078 - Provider product page
Provider: FineTest Biotech
Product name: ACD antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Component of the shelterin complex(telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: adrenocortical dysplasia homolog(Mo use)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ACD protein structure - FNab00078 shown in red.