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Cell line expression
Protein structure
HCST
Hematopoietic cell signal transducerDAP10, DKFZP586C1522, KAP10, PIK3AP
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  NB100-55403 |
1 references | Polyclonal |
WB
EL
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| Invitrogen Antibodies | BS-15430R |
Polyclonal |
WB
EL
IHC
FC
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| antibodies-online | ABIN188679 |
1 references | Polyclonal |
WB
EL
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| Abnova Corporation | PAB7141 |
1 references | Polyclonal |
WB
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