Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Immunohistochemistry [5]
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- Product number
- NB100-1793 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-1793, RRID:AB_2268669
- Product name
- Goat Polyclonal Pancreatic Polypeptide/PP Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Simian
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Development of monoclonal mouse antibodies that specifically recognize pancreatic polypeptide.
Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity.
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.
Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure.
Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes.
Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice.
Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats.
Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells.
Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.
Prostate stem cell antigen gene is expressed in islets of pancreas.
Vesicular monoamine transporter, type 2 (VMAT2) expression as it compares to insulin and pancreatic polypeptide in the head, body and tail of the human pancreas.
Pancreatic neurogenin 3-expressing cells are unipotent islet precursors.
Relationship between pancreatic vesicular monoamine transporter 2 (VMAT2) and insulin expression in human pancreas.
The gut and energy balance: visceral allies in the obesity wars.
Hara A, Nakagawa Y, Nakao K, Tamaki M, Ikemoto T, Shimada M, Matsuhisa M, Mizukami H, Maruyama N, Watada H, Fujitani Y
Endocrine journal 2019 May 28;66(5):459-468
Endocrine journal 2019 May 28;66(5):459-468
Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity.
Foo KS, Skowronski AA, Baum D, Firdessa-Fite R, Thams S, Shang L, Creusot RJ, LeDuc CA, Egli D, Leibel RL
Scientific reports 2019 Mar 21;9(1):4965
Scientific reports 2019 Mar 21;9(1):4965
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.
Lu TT, Heyne S, Dror E, Casas E, Leonhardt L, Boenke T, Yang CH, Sagar, Arrigoni L, Dalgaard K, Teperino R, Enders L, Selvaraj M, Ruf M, Raja SJ, Xie H, Boenisch U, Orkin SH, Lynn FC, Hoffman BG, Grün D, Vavouri T, Lempradl AM, Pospisilik JA
Cell metabolism 2018 Jun 5;27(6):1294-1308.e7
Cell metabolism 2018 Jun 5;27(6):1294-1308.e7
Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure.
Hull RL, Gibson RL, McNamara S, Deutsch GH, Fligner CL, Frevert CW, Ramsey BW, Sanda S
Diabetes care 2018 Apr;41(4):823-830
Diabetes care 2018 Apr;41(4):823-830
Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes.
Cinti F, Bouchi R, Kim-Muller JY, Ohmura Y, Sandoval PR, Masini M, Marselli L, Suleiman M, Ratner LE, Marchetti P, Accili D
The Journal of clinical endocrinology and metabolism 2016 Mar;101(3):1044-54
The Journal of clinical endocrinology and metabolism 2016 Mar;101(3):1044-54
Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice.
Kim-Muller JY, Fan J, Kim YJ, Lee SA, Ishida E, Blaner WS, Accili D
Nature communications 2016 Aug 30;7:12631
Nature communications 2016 Aug 30;7:12631
Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats.
Qian J, Block GD, Colwell CS, Matveyenko AV
Diabetes 2013 Oct;62(10):3469-78
Diabetes 2013 Oct;62(10):3469-78
Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells.
Lee J, Sugiyama T, Liu Y, Wang J, Gu X, Lei J, Markmann JF, Miyazaki S, Miyazaki J, Szot GL, Bottino R, Kim SK
eLife 2013 Nov 19;2:e00940
eLife 2013 Nov 19;2:e00940
Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.
Sugiyama T, Benitez CM, Ghodasara A, Liu L, McLean GW, Lee J, Blauwkamp TA, Nusse R, Wright CV, Gu G, Kim SK
Proceedings of the National Academy of Sciences of the United States of America 2013 Jul 30;110(31):12691-6
Proceedings of the National Academy of Sciences of the United States of America 2013 Jul 30;110(31):12691-6
Prostate stem cell antigen gene is expressed in islets of pancreas.
Ono H, Yanagihara K, Sakamoto H, Yoshida T, Saeki N
Anatomy & cell biology 2012 Sep;45(3):149-54
Anatomy & cell biology 2012 Sep;45(3):149-54
Vesicular monoamine transporter, type 2 (VMAT2) expression as it compares to insulin and pancreatic polypeptide in the head, body and tail of the human pancreas.
Freeby M, Ichise M, Harris PE
Islets 2012 Nov-Dec;4(6):393-7
Islets 2012 Nov-Dec;4(6):393-7
Pancreatic neurogenin 3-expressing cells are unipotent islet precursors.
Desgraz R, Herrera PL
Development (Cambridge, England) 2009 Nov;136(21):3567-74
Development (Cambridge, England) 2009 Nov;136(21):3567-74
Relationship between pancreatic vesicular monoamine transporter 2 (VMAT2) and insulin expression in human pancreas.
Saisho Y, Harris PE, Butler AE, Galasso R, Gurlo T, Rizza RA, Butler PC
Journal of molecular histology 2008 Oct;39(5):543-51
Journal of molecular histology 2008 Oct;39(5):543-51
The gut and energy balance: visceral allies in the obesity wars.
Badman MK, Flier JS
Science (New York, N.Y.) 2005 Mar 25;307(5717):1909-14
Science (New York, N.Y.) 2005 Mar 25;307(5717):1909-14
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Pancreatic Polypeptide/PP Antibody [NB100-1793] - Adult macaque pancrease paraffin sections following standard protocols. IHC-P image submitted by a verified customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: Pancreatic Polypeptide/PP Antibody [NB100-1793] - Analysis of Pancreatic Polypeptide in mouse adult pancreas tissue. IHC-Fr image submitted by a verified customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Pancreatic Polypeptide/PP Antibody [NB100-1793] - Staining of paraffin embedded Human Pancreas with antibody at 3 ug/mL. Microwaved antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Pancreatic Polypeptide/PP Antibody [NB100-1793] - Staining of paraffin embedded Human Intestine with antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Pancreatic Polypeptide/PP Antibody [NB100-1793] - Staining of paraffin embedded Human Pancreas with antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.