Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 21316-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21316-1-AP, RRID:AB_10733105
- Product name
- C5aR antibody
- Antibody type
- Polyclonal
- Description
- C5aR antibody (Cat. #21316-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HSP90-Mediates Liraglutide Preconditioning-Induced Cardioprotection by Inhibiting C5a and NF-κB.
C5a complement receptor modulates odontogenic dental pulp stem cell differentiation under hypoxia.
Linking Complement C3 and B Cells in Nasal Polyposis.
Complement Activation and Organ Damage After Trauma-Differential Immune Response Based on Surgical Treatment Strategy.
The hepatocyte-specifically expressed lnc-HSER alleviates hepatic fibrosis by inhibiting hepatocyte apoptosis and epithelial-mesenchymal transition.
N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor.
Lung injury after asphyxia and hemorrhagic shock in newborn piglets: Analysis of structural and inflammatory changes.
Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS.
RNA sequencing screening of differentially expressed genes after spinal cord injury.
Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis.
Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43.
Cardiac Depression in Pigs after Multiple Trauma - Characterization of Posttraumatic Structural and Functional Alterations.
Nerve Growth Factor Secretion From Pulp Fibroblasts is Modulated by Complement C5a Receptor and Implied in Neurite Outgrowth.
Complement is a central mediator of radiotherapy-induced tumor-specific immunity and clinical response.
He ST, Wang DX, Meng JJ, Cheng XF, Bi Q, Zhong GQ, Tu RH
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2021 Oct 20;:1-9
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2021 Oct 20;:1-9
C5a complement receptor modulates odontogenic dental pulp stem cell differentiation under hypoxia.
Pasiewicz R, Valverde Y, Narayanan R, Kim JH, Irfan M, Lee NS, George A, Cooper LF, Alapati SB, Chung S
Connective tissue research 2021 May 24;:1-10
Connective tissue research 2021 May 24;:1-10
Linking Complement C3 and B Cells in Nasal Polyposis.
Werner U, Künstner A, Drenckhan M, Pries R, Bruchhage KL, Busch HS, Bachert C, Wollenberg B
Journal of immunology research 2020;2020:4832189
Journal of immunology research 2020;2020:4832189
Complement Activation and Organ Damage After Trauma-Differential Immune Response Based on Surgical Treatment Strategy.
Lackner I, Weber B, Baur M, Fois G, Gebhard F, Pfeifer R, Cinelli P, Halvachizadeh S, Lipiski M, Cesarovic N, Schrezenmeier H, Huber-Lang M, Pape HC, Kalbitz M
Frontiers in immunology 2020;11:64
Frontiers in immunology 2020;11:64
The hepatocyte-specifically expressed lnc-HSER alleviates hepatic fibrosis by inhibiting hepatocyte apoptosis and epithelial-mesenchymal transition.
Zhang K, Zhang M, Yao Q, Han X, Zhao Y, Zheng L, Li G, Liu Q, Chang Y, Zhang P, Cui H, Shi Z, Chen T, Yao Z, Han T, Hong W
Theranostics 2019;9(25):7566-7582
Theranostics 2019;9(25):7566-7582
N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor.
Huang S, You J, Wang K, Li Y, Zhang Y, Wei H, Liang X, Liu Y
BioMed research international 2019;2019:4805853
BioMed research international 2019;2019:4805853
Lung injury after asphyxia and hemorrhagic shock in newborn piglets: Analysis of structural and inflammatory changes.
Weber B, Mendler MR, Lackner I, von Zelewski A, Höfler S, Baur M, Braun CK, Hummler H, Schwarz S, Pressmar J, Kalbitz M
PloS one 2019;14(7):e0219211
PloS one 2019;14(7):e0219211
Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS.
Liu M, Mu H, Peng W, Zhao L, Hu W, Jiang Z, Gao L, Cao X, Li N, Han J
International journal of molecular medicine 2019 Sep;44(3):823-834
International journal of molecular medicine 2019 Sep;44(3):823-834
RNA sequencing screening of differentially expressed genes after spinal cord injury.
Li Y, Chen Y, Li X, Wu J, Pan JY, Cai RX, Yang RY, Wang XD
Neural regeneration research 2019 Sep;14(9):1583-1593
Neural regeneration research 2019 Sep;14(9):1583-1593
Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis.
Xu P, Werner JU, Milerski S, Hamp CM, Kuzenko T, Jähnert M, Gottmann P, de Roy L, Warnecke D, Abaei A, Palmer A, Huber-Lang M, Dürselen L, Rasche V, Schürmann A, Wabitsch M, Knippschild U
Frontiers in physiology 2018;9:674
Frontiers in physiology 2018;9:674
Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43.
Kalbitz M, Amann EM, Bosch B, Palmer A, Schultze A, Pressmar J, Weber B, Wepler M, Gebhard F, Schrezenmeier H, Brenner R, Huber-Lang M
PloS one 2017;12(11):e0187270
PloS one 2017;12(11):e0187270
Cardiac Depression in Pigs after Multiple Trauma - Characterization of Posttraumatic Structural and Functional Alterations.
Kalbitz M, Schwarz S, Weber B, Bosch B, Pressmar J, Hoenes FM, Braun CK, Horst K, Simon TP, Pfeifer R, Störmann P, Hummler H, Gebhard F, Pape HC, Huber-Lang M, Hildebrand F, TREAT Research Group.
Scientific reports 2017 Dec 19;7(1):17861
Scientific reports 2017 Dec 19;7(1):17861
Nerve Growth Factor Secretion From Pulp Fibroblasts is Modulated by Complement C5a Receptor and Implied in Neurite Outgrowth.
Chmilewsky F, Ayaz W, Appiah J, About I, Chung SH
Scientific reports 2016 Aug 19;6:31799
Scientific reports 2016 Aug 19;6:31799
Complement is a central mediator of radiotherapy-induced tumor-specific immunity and clinical response.
Surace L, Lysenko V, Fontana AO, Cecconi V, Janssen H, Bicvic A, Okoniewski M, Pruschy M, Dummer R, Neefjes J, Knuth A, Gupta A, van den Broek M
Immunity 2015 Apr 21;42(4):767-77
Immunity 2015 Apr 21;42(4):767-77
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 21316-1-AP(C5AR1 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using C5AR1 antibody 21316-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 21316-1-AP(C5AR1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 21316-1-AP(C5AR1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue