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Learn11944-1-AP
antibody from Proteintech Group
Targeting: STEAP4
FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 11944-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11944-1-AP, RRID:AB_2197868
- Product name
- STEAP4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STEAP4 antibody (Cat. #11944-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Discovery and Pharmacological Evaluation of STEAP4 as a Novel Target for HER2 Overexpressing Breast Cancer.
The expression of STEAP4 in peripheral blood predicts the outcome of septic patients.
Overexpressing STAMP2 attenuates diabetic renal injuries via upregulating autophagy in diabetic rats.
Hepatic STAMP2 mediates recombinant FGF21-induced improvement of hepatic iron overload in nonalcoholic fatty liver disease.
Hepatic Steatosis Alleviated in Diabetic Mice upon Dietary Exposure to Fibroin via Transgenic Rice: Potential STAMP2 Involvement in Hepatocytes.
The six-transmembrane protein Stamp2 ameliorates pulmonary vascular remodeling and pulmonary hypertension in mice.
Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis.
Dietary Exposure to Transgenic Rice Expressing the Spider Silk Protein Fibroin Reduces Blood Glucose Levels in Diabetic Mice: The Potential Role of Insulin Receptor Substrate-1 Phosphorylation in Adipocytes.
Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27.
Palmitate induces lipoapoptosis in Schwann cells through ROS generation-mediated STAMP2 downregulation.
Effect of Omega-3 Fatty Acid on STAMP2 Expression in the Heart and Kidney of 5/6 Nephrectomy Rat Model.
Cilostazol Improves HFD-Induced Hepatic Steatosis by Upregulating Hepatic STAMP2 Expression through AMPK.
Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.
Overexpressing STAMP2 attenuates adipose tissue angiogenesis and insulin resistance in diabetic ApoE-/- /LDLR-/- mouse via a PPARγ/CD36 pathway.
Six-transmembrane epithelial antigens of the prostate comprise a novel inflammatory nexus in patients with pustular skin disorders.
Genome-wide DNA methylation analysis in hepatocellular carcinoma.
STAMP2 increases oxidative stress and is critical for prostate cancer.
Hepatic STAMP2 alleviates high fat diet-induced hepatic steatosis and insulin resistance.
Differential expression and function of stamp family proteins in adipocyte differentiation.
Overexpressing STAMP2 improves insulin resistance in diabetic ApoE⁻/⁻/LDLR⁻/⁻ mice via macrophage polarization shift in adipose tissues.
Six-transmembrane epithelial antigen of prostate 4 and neutrophil gelatinase-associated lipocalin expression in visceral adipose tissue is related to iron status and inflammation in human obesity.
Induction of STEAP4 correlates with 1,25-dihydroxyvitamin D3 stimulation of adipogenesis in mesenchymal progenitor cells derived from human adipose tissue.
Interleukin-1beta is a positive regulator of TIARP/STAMP2 gene and protein expression in adipocytes in vitro.
Expression of six transmembrane protein of prostate 2 in human adipose tissue associates with adiposity and insulin resistance.
Orfanou IM, Argyros O, Papapetropoulos A, Tseleni-Balafouta S, Vougas K, Tamvakopoulos C
Frontiers in oncology 2021;11:608201
Frontiers in oncology 2021;11:608201
The expression of STEAP4 in peripheral blood predicts the outcome of septic patients.
Jiang H, Dong Y, Yan D, Wu Y, Wang Y, Ren Y, Mao G, Liang G, Liu W, Zhou Y, Huang Z, Qi L
Annals of translational medicine 2021 Oct;9(20):1519
Annals of translational medicine 2021 Oct;9(20):1519
Overexpressing STAMP2 attenuates diabetic renal injuries via upregulating autophagy in diabetic rats.
Song FQ, Song M, Ma WX, Gao Z, Ti Y, Zhang X, Hu BA, Zhong M, Zhang W, Yu Y
Biochemical and biophysical research communications 2021 Nov 19;579:47-53
Biochemical and biophysical research communications 2021 Nov 19;579:47-53
Hepatic STAMP2 mediates recombinant FGF21-induced improvement of hepatic iron overload in nonalcoholic fatty liver disease.
Kim HY, Kwon WY, Park JB, Lee MH, Oh YJ, Suh S, Baek YH, Jeong JS, Yoo YH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12354-12366
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):12354-12366
Hepatic Steatosis Alleviated in Diabetic Mice upon Dietary Exposure to Fibroin via Transgenic Rice: Potential STAMP2 Involvement in Hepatocytes.
Park JE, Jeong YJ, Kim HY, Yoo YH, Lee KS, Yang WT, Kim DH, Kim JM
Development & reproduction 2020 Sep;24(3):231-239
Development & reproduction 2020 Sep;24(3):231-239
The six-transmembrane protein Stamp2 ameliorates pulmonary vascular remodeling and pulmonary hypertension in mice.
Batool M, Berghausen EM, Zierden M, Vantler M, Schermuly RT, Baldus S, Rosenkranz S, Ten Freyhaus H
Basic research in cardiology 2020 Nov 13;115(6):68
Basic research in cardiology 2020 Nov 13;115(6):68
Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis.
Liao Y, Zhao J, Bulek K, Tang F, Chen X, Cai G, Jia S, Fox PL, Huang E, Pizarro TT, Kalady MF, Jackson MW, Bao S, Sen GC, Stark GR, Chang CJ, Li X
Nature communications 2020 Feb 14;11(1):900
Nature communications 2020 Feb 14;11(1):900
Dietary Exposure to Transgenic Rice Expressing the Spider Silk Protein Fibroin Reduces Blood Glucose Levels in Diabetic Mice: The Potential Role of Insulin Receptor Substrate-1 Phosphorylation in Adipocytes.
Park JE, Jeong YJ, Park JB, Kim HY, Yoo YH, Lee KS, Yang WT, Kim DH, Kim JM
Development & reproduction 2019 Sep;23(3):223-229
Development & reproduction 2019 Sep;23(3):223-229
Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27.
Lee SW, Rho JH, Lee SY, Chung WT, Oh YJ, Kim JH, Yoo SH, Kwon WY, Bae JY, Seo SY, Sun H, Kim HY, Yoo YH
Bone research 2018;6:20
Bone research 2018;6:20
Palmitate induces lipoapoptosis in Schwann cells through ROS generation-mediated STAMP2 downregulation.
Lee SW, Park JB, Kim HJ, Kim HY, Lee SY, Chung WT, Shin YK, Park HT, Rho JH, Yoo YH
Biochemical and biophysical research communications 2018 Sep 10;503(3):1260-1266
Biochemical and biophysical research communications 2018 Sep 10;503(3):1260-1266
Effect of Omega-3 Fatty Acid on STAMP2 Expression in the Heart and Kidney of 5/6 Nephrectomy Rat Model.
Lee HW, Lee SM, Lee MH, Son YK, Kim SE, An WS
Marine drugs 2018 Oct 23;16(11)
Marine drugs 2018 Oct 23;16(11)
Cilostazol Improves HFD-Induced Hepatic Steatosis by Upregulating Hepatic STAMP2 Expression through AMPK.
Oh YJ, Kim HY, Lee MH, Suh SH, Choi Y, Nam TG, Kwon WY, Lee SY, Yoo YH
Molecular pharmacology 2018 Dec;94(6):1401-1411
Molecular pharmacology 2018 Dec;94(6):1401-1411
Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.
Xue X, Bredell BX, Anderson ER, Martin A, Mays C, Nagao-Kitamoto H, Huang S, Győrffy B, Greenson JK, Hardiman K, Spence JR, Kamada N, Shah YM
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 7;114(45):E9608-E9617
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 7;114(45):E9608-E9617
Overexpressing STAMP2 attenuates adipose tissue angiogenesis and insulin resistance in diabetic ApoE-/- /LDLR-/- mouse via a PPARγ/CD36 pathway.
Wang F, Han L, Qin RR, Zhang YY, Wang D, Wang ZH, Tang MX, Zhang Y, Zhong M, Zhang W
Journal of cellular and molecular medicine 2017 Dec;21(12):3298-3308
Journal of cellular and molecular medicine 2017 Dec;21(12):3298-3308
Six-transmembrane epithelial antigens of the prostate comprise a novel inflammatory nexus in patients with pustular skin disorders.
Liang Y, Xing X, Beamer MA, Swindell WR, Sarkar MK, Roberts LW, Voorhees JJ, Kahlenberg JM, Harms PW, Johnston A, Gudjonsson JE
The Journal of allergy and clinical immunology 2017 Apr;139(4):1217-1227
The Journal of allergy and clinical immunology 2017 Apr;139(4):1217-1227
Genome-wide DNA methylation analysis in hepatocellular carcinoma.
Yamada N, Yasui K, Dohi O, Gen Y, Tomie A, Kitaichi T, Iwai N, Mitsuyoshi H, Sumida Y, Moriguchi M, Yamaguchi K, Nishikawa T, Umemura A, Naito Y, Tanaka S, Arii S, Itoh Y
Oncology reports 2016 Apr;35(4):2228-36
Oncology reports 2016 Apr;35(4):2228-36
STAMP2 increases oxidative stress and is critical for prostate cancer.
Jin Y, Wang L, Qu S, Sheng X, Kristian A, Mælandsmo GM, Pällmann N, Yuca E, Tekedereli I, Gorgulu K, Alpay N, Sood A, Lopez-Berestein G, Fazli L, Rennie P, Risberg B, Wæhre H, Danielsen HE, Ozpolat B, Saatcioglu F
EMBO molecular medicine 2015 Mar;7(3):315-31
EMBO molecular medicine 2015 Mar;7(3):315-31
Hepatic STAMP2 alleviates high fat diet-induced hepatic steatosis and insulin resistance.
Kim HY, Park SY, Lee MH, Rho JH, Oh YJ, Jung HU, Yoo SH, Jeong NY, Lee HJ, Suh S, Seo SY, Cheong J, Jeong JS, Yoo YH
Journal of hepatology 2015 Aug;63(2):477-85
Journal of hepatology 2015 Aug;63(2):477-85
Differential expression and function of stamp family proteins in adipocyte differentiation.
Sikkeland J, Saatcioglu F
PloS one 2013;8(7):e68249
PloS one 2013;8(7):e68249
Overexpressing STAMP2 improves insulin resistance in diabetic ApoE⁻/⁻/LDLR⁻/⁻ mice via macrophage polarization shift in adipose tissues.
Han L, Tang MX, Ti Y, Wang ZH, Wang J, Ding WY, Wang H, Zhang Y, Zhang W, Zhong M
PloS one 2013;8(11):e78903
PloS one 2013;8(11):e78903
Six-transmembrane epithelial antigen of prostate 4 and neutrophil gelatinase-associated lipocalin expression in visceral adipose tissue is related to iron status and inflammation in human obesity.
Catalán V, Gómez-Ambrosi J, Rodríguez A, Ramírez B, Rotellar F, Valentí V, Silva C, Gil MJ, Salvador J, Frühbeck G
European journal of nutrition 2013 Sep;52(6):1587-95
European journal of nutrition 2013 Sep;52(6):1587-95
Induction of STEAP4 correlates with 1,25-dihydroxyvitamin D3 stimulation of adipogenesis in mesenchymal progenitor cells derived from human adipose tissue.
Narvaez CJ, Simmons KM, Brunton J, Salinero A, Chittur SV, Welsh JE
Journal of cellular physiology 2013 Oct;228(10):2024-36
Journal of cellular physiology 2013 Oct;228(10):2024-36
Interleukin-1beta is a positive regulator of TIARP/STAMP2 gene and protein expression in adipocytes in vitro.
Kralisch S, Sommer G, Weise S, Lipfert J, Lossner U, Kamprad M, Schröck K, Bluher M, Stumvoll M, Fasshauer M
FEBS letters 2009 Apr 2;583(7):1196-200
FEBS letters 2009 Apr 2;583(7):1196-200
Expression of six transmembrane protein of prostate 2 in human adipose tissue associates with adiposity and insulin resistance.
Arner P, Stenson BM, Dungner E, Näslund E, Hoffstedt J, Ryden M, Dahlman I
The Journal of clinical endocrinology and metabolism 2008 Jun;93(6):2249-54
The Journal of clinical endocrinology and metabolism 2008 Jun;93(6):2249-54
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- 3T3-L1 cells were subjected to SDS PAGE followed by western blot with 11944-1-AP(STEAP4 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-STEAP4 (IP:11944-1-AP, 4ug; Detection:11944-1-AP 1:1000) with A549 cells lysate 1600ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STEAP4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human STEAP4. This antibody recognizes human, mouse, rat antigen. The STEAP4 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
