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Learn10-4165-25
antibody from ABEOMICS Inc.
Targeting: MUL1
C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 10-4165-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-MUL1 Antibody
- Antibody type
- Monoclonal
- Description
- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant MUL1 p
rotein (amino acids 146-352) was us
ed as the immunogen for this antibo
dy.- Isotype
- IgG
- Antibody clone number
- ABM4F71
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of MUL1. Anti-MUL1 antibody (Clone: ABM4F71) was tested at 4 µg/ml on human SKM lysate.
- Protocol
- Protocol
