Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15140-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15140-1-AP, RRID:AB_2109890
- Product name
- GLO1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GLO1 antibody (Cat. #15140-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Butyrate increases methylglyoxal production through regulation of the JAK2/Stat3/Nrf2/Glo1 pathway in castration‑resistant prostate cancer cells.
Methylglyoxal accumulation contributes to accelerated brain aging in spontaneously hypertensive rats.
Protective effects of Huang-Qi-Ge-Gen decoction against diabetic liver injury through regulating PI3K/AKT/Nrf2 pathway and metabolic profiling.
Protective effect of heat-processed Gynostemma pentaphyllum on high fat diet-induced glucose metabolic disorders mice.
Glyoxalase 1 inhibitor BBGC suppresses the progression of chronic lymphocytic leukemia and promotes the efficacy of Palbociclib.
Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy.
Nordihydroguaiaretic acid inhibits glyoxalase I, and causes the accumulation of methylglyoxal followed by cell-growth inhibition.
Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice.
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.
Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells.
Hsia YJ, Lin ZM, Zhang T, Chou TC
Oncology reports 2024 May;51(5)
Oncology reports 2024 May;51(5)
Methylglyoxal accumulation contributes to accelerated brain aging in spontaneously hypertensive rats.
Zhang WY, Zhao CM, Wang CS, Xie X, Li YQ, Chen BB, Feng L, Jiang P
Free radical biology & medicine 2024 Jan;210:108-119
Free radical biology & medicine 2024 Jan;210:108-119
Protective effects of Huang-Qi-Ge-Gen decoction against diabetic liver injury through regulating PI3K/AKT/Nrf2 pathway and metabolic profiling.
Zhang ZT, Liang QF, Wang X, Wang RS, Duan TT, Wang SM, Tang D
Journal of ethnopharmacology 2024 Apr 6;323:117647
Journal of ethnopharmacology 2024 Apr 6;323:117647
Protective effect of heat-processed Gynostemma pentaphyllum on high fat diet-induced glucose metabolic disorders mice.
Xie JB, Xie P, Guo M, Li FF, Xiao MY, Qi YS, Pei WJ, Luo HT, Gu YL, Piao XL
Frontiers in pharmacology 2023;14:1215150
Frontiers in pharmacology 2023;14:1215150
Glyoxalase 1 inhibitor BBGC suppresses the progression of chronic lymphocytic leukemia and promotes the efficacy of Palbociclib.
Tang J, Zhong J, Yang Z, Su Q, Mo W
Biochemical and biophysical research communications 2023 Apr 2;650:96-102
Biochemical and biophysical research communications 2023 Apr 2;650:96-102
Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy.
Luo L, Luo J, Cai Y, Fu M, Li W, Shi L, Liu J, Dong R, Xu X, Tu L, Yang Y
Pharmacological research 2022 Sep;183:106367
Pharmacological research 2022 Sep;183:106367
Nordihydroguaiaretic acid inhibits glyoxalase I, and causes the accumulation of methylglyoxal followed by cell-growth inhibition.
Watanabe M, Toyomura T, Ikegami R, Suwaki Y, Sada M, Wake H, Nishinaka T, Hatipoglu OF, Takahashi H, Nishibori M, Mori S
Molecular biology reports 2022 Nov;49(11):10499-10507
Molecular biology reports 2022 Nov;49(11):10499-10507
Protective effects of Huang-Lian-Jie-Du Decoction on diabetic nephropathy through regulating AGEs/RAGE/Akt/Nrf2 pathway and metabolic profiling in db/db mice.
Tang D, He WJ, Zhang ZT, Shi JJ, Wang X, Gu WT, Chen ZQ, Xu YH, Chen YB, Wang SM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153777
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153777
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Tian S, Feng J, Cao Y, Shen S, Cai Y, Yang D, Yan R, Wang L, Zhang H, Zhong X, Gao P
Life science alliance 2019 Oct;2(5)
Life science alliance 2019 Oct;2(5)
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.
Allen SP, Hall B, Woof R, Francis L, Gatto N, Shaw AC, Myszczynska M, Hemingway J, Coldicott I, Willcock A, Job L, Hughes RM, Boschian C, Bayatti N, Heath PR, Bandmann O, Mortiboys H, Ferraiuolo L, Shaw PJ
Brain : a journal of neurology 2019 Dec 1;142(12):3771-3790
Brain : a journal of neurology 2019 Dec 1;142(12):3771-3790
Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells.
Tamori S, Nozaki Y, Motomura H, Nakane H, Katayama R, Onaga C, Kikuchi E, Shimada N, Suzuki Y, Noike M, Hara Y, Sato K, Sato T, Yamamoto K, Hanawa T, Imai M, Abe R, Yoshimori A, Takasawa R, Tanuma SI, Akimoto K
Oncotarget 2018 Nov 23;9(92):36515-36529
Oncotarget 2018 Nov 23;9(92):36515-36529
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GLO1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GLO1. This antibody recognizes human, mouse, rat antigen. The GLO1 antibody has been validated for the following applications: ELISA, WB analysis.