APR06499G

antibody from Leading Biology
Targeting: IL34 C16orf77, IL-34, MGC34647
Provider product page for APR06499G
Western blot

Antibody data

Product number
APR06499G - Provider product page
Provider
Leading Biology
Product name
IL-34 Antibody
Antibody type
Polyclonal
Description
IL-34 Antibody: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
IL34 protein structure - APR06499G shown in red.