ABIN350459

antibody from antibodies-online

Targeting: OPN4 melanopsin, MOP

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN350459

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN350459, RRID:AB_10785986

Product name

anti-Opsin 4 (OPN4) (AA 420-470) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide from aa region 420-470 of human melanopsin conjugated to an immunogenic carrier protein was used as the antigen.

Description

Whole serum

Reactivity

Human

Host

Rabbit

Epitope

AA 420-470

Vial size

100 μL

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

Melanopsin triggers the release of internal calcium stores in response to light.

Kumbalasiri T, Rollag MD, Isoldi MC, Castrucci AM, Provencio I
Photochemistry and photobiology 2007 Mar-Apr;83(2):273-9

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Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN.

Dacey DM, Liao HW, Peterson BB, Robinson FR, Smith VC, Pokorny J, Yau KW, Gamlin PD
Nature 2005 Feb 17;433(7027):749-54

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Induction of photosensitivity by heterologous expression of melanopsin.

Qiu X, Kumbalasiri T, Carlson SM, Wong KY, Krishna V, Provencio I, Berson DM
Nature 2005 Feb 17;433(7027):745-9

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Addition of human melanopsin renders mammalian cells photoresponsive.

Melyan Z, Tarttelin EE, Bellingham J, Lucas RJ, Hankins MW
Nature 2005 Feb 17;433(7027):741-5