Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- H00011277-D01P - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#H00011277-D01P, RRID:AB_1716449
- Product name
- TREX1 purified MaxPab rabbit polyclonal antibody (D01P)
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against a full-length human TREX1 protein.
- Antigen sequence
MGPGARRQGRIVQGRPEMCFCPPPTPLPPLRILTL
GTHTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLI
FFDMEATGLPFSQPKVTELCLLAVHRCALESPPTS
QGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEIT
GLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWC
LVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDS
ITALKALERASSPSEHGPRKSYSLGSIYTRLYGQS
PPDSHTAEGDVLALLSICQWRPQALLRWVDAHARP
FGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNT
SPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLA
ILTLAVATLYGLSLATPGE- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Submitted references Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs.
Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.
Tomicic MT, Aasland D, Nikolova T, Kaina B, Christmann M
Biochimica et biophysica acta 2013 Aug;1833(8):1832-43
Biochimica et biophysica acta 2013 Aug;1833(8):1832-43
Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.
Christmann M, Tomicic MT, Aasland D, Berdelle N, Kaina B
Nucleic acids research 2010 Oct;38(19):6418-32
Nucleic acids research 2010 Oct;38(19):6418-32
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- TREX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in K-562.
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- TREX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in Raw 264.7.