abx011331
antibody from Abbexa
Targeting: PEG10
HB-1, KIAA1051, Mar2, Mart2, MEF3L, RGAG3, RTL2, SIRH1
Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- abx011331 - Provider product page
- Provider
- Abbexa
- Product name
- Retrotransposon-Derived Protein PEG10 (PEG10) Antibody
- Antibody type
- Monoclonal
- Description
- PEG10: paternally expressed 10. This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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