APR04401G

antibody from Leading Biology

Targeting: MRPL11

Western blot (Recommended by provider)

Antibody Data

Product number

APR04401G

Provider

Leading Biology

Product name

MRPL11 Antibody (N-term)

Antibody type

Polyclonal

Description

Mammalian mitochondrial ribosomal proteins are encoded bynuclear genes and help in protein synthesis within themitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of asmall 28S subunit and a large 39S subunit. They have an estimated75% protein to rRNA composition compared to prokaryotic ribosomes,where this ratio is reversed. Another difference between mammalianmitoribosomes and prokaryotic ribosomes is that the latter containa 5S rRNA. Among different species, the proteins comprising themitoribosome differ greatly in sequence, and sometimes inbiochemical properties, which prevents easy recognition by sequencehomology. This gene encodes a 39S subunit protein. Sequenceanalysis identified three transcript variants that encode differentisoforms. Pseudogenes corresponding to this gene are found onchromosomes 5q and 12q.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.