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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB245F - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal IFN-alpha/beta R1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human IFN-alpha/beta R1 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) IFN-gamma R1, rhIFN-gamma R2, recombinant mouse IFN-alpha/beta R2, rhIL-10 R beta , rhIL-10 R alpha , or rhIL-20 R beta .
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells.
Interferon-alpha triggers B cell effector 1 (Be1) commitment.
Human metapneumovirus inhibits IFN-alpha signaling through inhibition of STAT1 phosphorylation.
Stone AE, Giugliano S, Schnell G, Cheng L, Leahy KF, Golden-Mason L, Gale M Jr, Rosen HR
PLoS pathogens 2013;9(4):e1003316
PLoS pathogens 2013;9(4):e1003316
Interferon-alpha triggers B cell effector 1 (Be1) commitment.
de Goër de Herve MG, Durali D, Dembele B, Giuliani M, Tran TA, Azzarone B, Eid P, Tardieu M, Delfraissy JF, Taoufik Y
PloS one 2011 Apr 29;6(4):e19366
PloS one 2011 Apr 29;6(4):e19366
Human metapneumovirus inhibits IFN-alpha signaling through inhibition of STAT1 phosphorylation.
Dinwiddie DL, Harrod KS
American journal of respiratory cell and molecular biology 2008 Jun;38(6):661-70
American journal of respiratory cell and molecular biology 2008 Jun;38(6):661-70
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Detection of IFN-alpha/beta R1 in U937 Human Cell Line by Flow Cytometry. U937 human histiocytic lymphoma cell line was stained with Mouse Anti-Human IFN-alpha/beta R1 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB245F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.
