Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- ELISA [1]
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- Product number
- H00006903-M04 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00006903-M04, RRID:AB_1147198
- Product name
- Mouse Monoclonal TBCC Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. TBCC - tubulin-specific chaperone c (3D3)
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references The solution structure of the N-terminal domain of human tubulin binding cofactor C reveals a platform for tubulin interaction.
Silencing of tubulin binding cofactor C modifies microtubule dynamics and cell cycle distribution and enhances sensitivity to gemcitabine in breast cancer cells.
Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells.
Garcia-Mayoral MF, CastaƱo R, Fanarraga ML, Zabala JC, Rico M, Bruix M
PloS one 2011;6(10):e25912
PloS one 2011;6(10):e25912
Silencing of tubulin binding cofactor C modifies microtubule dynamics and cell cycle distribution and enhances sensitivity to gemcitabine in breast cancer cells.
Hage-Sleiman R, Herveau S, Matera EL, Laurier JF, Dumontet C
Molecular cancer therapeutics 2011 Feb;10(2):303-12
Molecular cancer therapeutics 2011 Feb;10(2):303-12
Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells.
Hage-Sleiman R, Herveau S, Matera EL, Laurier JF, Dumontet C
BMC cancer 2010 Apr 12;10:135
BMC cancer 2010 Apr 12;10:135
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Sandwich ELISA: TBCC Antibody (3D3) [H00006903-M04] - Detection limit for recombinant GST tagged TBCC is 0.3 ng/ml as a capture antibody.