Tissue expression
Cell line expression
Protein structure

CTSF

Cathepsin F
CATSF, CLN13 
Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
311 antibodies from 34 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
45 antibodies
R&D Systems
5 antibodies
Proteintech Group
1 antibody
antibodies-online
105 antibodies
OriGene
4 antibodies
Abgent
2 antibodies
Invitrogen Antibodies
9 antibodies
Biorbyt
29 antibodies
St John's Laboratory
2 antibodies
Aviva Systems Biology
2 antibodies
FineTest Biotech
1 antibody
NovoPro Bioscience Inc.
1 antibody
Abnova Corporation
5 antibodies
ProSci
2 antibodies
Everest Biotech
1 antibody
GeneTex
4 antibodies
Cusabio Biotech Co., Ltd
5 antibodies
Antibodies.com
1 antibody
Acris Antibodies GmbH
8 antibodies
NSJ Bioreagents
1 antibody
MyBioSource
11 antibodies
Arigo
1 antibody
Bioworld Technology, Inc
1 antibody
Leading Biology
3 antibodies
Affinity Biosciences
1 antibody
Boster Biological Technology
1 antibody
RabMAbs
1 antibody
Creative Diagnostics
3 antibodies
Creative Biolabs
7 antibodies
United States Biological
15 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Abbexa
8 antibodies
RayBiotech, Inc.
1 antibody