MB0168

antibody from Bioworld Technology, Inc
Targeting: NFE2L1 FLJ00380, LCR-F1, NRF1, TCF11
Provider product page for MB0168

Antibody data

Product number
MB0168 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NFE2L1 monoclonal antibody
Antibody type
Monoclonal
Antigen
Recombinant full length Human NFE2L1.
Description
The NF-E2 DNA binding protein is composed of two subunits, p45 and MafK, and it regulates expression of globin genes in developing erythroid cells through interaction with Maf recognition elements (MAREs). A family of NF-E2-related proteins, which are collectively known as the cap £¦n£ª collar (CNC) family and include NFE2L1 (also designated TCF11), Nrf2 and Nrf3, are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE sequences. The Nrf proteins also bind the antioxidant response element (ARE) and are implicated in the regulation of detoxification enzymes and the oxidative stress response. They do so by heterodimerizing with Jun family members (c-Jun, Jun B and Jun D) to activate gene expression, specifically the detoxifying enzyme NQO1.
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NFE2L1 protein structure - MB0168 shown in red.