Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 23247-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- IFIT1 antibody
- Antibody type
- Polyclonal
- Description
- IFIT1 antibody (Cat. #23247-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Human IFIT3 Protein Induces Interferon Signaling and Inhibits Adenovirus Immediate Early Gene Expression.
Interferon-Lambda Intranasal Protection and Differential Sex Pathology in a Murine Model of SARS-CoV-2 Infection.
Mechanism of berberine in treating Helicobacter pylori induced chronic atrophic gastritis through IRF8-IFN-γ signaling axis suppressing.
A RIG-I-like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination.
Human Papillomavirus 16 E5 Inhibits Interferon Signaling and Supports Episomal Viral Maintenance.
Suppression of Stromal Interferon Signaling by Human Papillomavirus 16.
Label-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-α Identifies Antiviral Proteins Enriched in Exosomes.
Alpha/beta interferon receptor deficiency in mice significantly enhances susceptibility of the animals to pseudorabies virus infection.
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
Herpes Simplex Virus 1 Tegument Protein UL41 Counteracts IFIT3 Antiviral Innate Immunity.
Li TH, Zhao BB, Qin C, Wang YY, Li ZR, Cao HT, Yang XY, Zhou XT, Wang WB
Cellular oncology (Dordrecht) 2021 Dec;44(6):1425-1437
Cellular oncology (Dordrecht) 2021 Dec;44(6):1425-1437
Human IFIT3 Protein Induces Interferon Signaling and Inhibits Adenovirus Immediate Early Gene Expression.
Chikhalya A, Dittmann M, Zheng Y, Sohn SY, Rice CM, Hearing P
mBio 2021 Dec 21;12(6):e0282921
mBio 2021 Dec 21;12(6):e0282921
Interferon-Lambda Intranasal Protection and Differential Sex Pathology in a Murine Model of SARS-CoV-2 Infection.
Sohn SY, Hearing J, Mugavero J, Kirillov V, Gorbunova E, Helminiak L, Mishra S, Mackow E, Hearing P, Reich NC, Kim HK
mBio 2021 Dec 21;12(6):e0275621
mBio 2021 Dec 21;12(6):e0275621
Mechanism of berberine in treating Helicobacter pylori induced chronic atrophic gastritis through IRF8-IFN-γ signaling axis suppressing.
Yang T, Wang R, Zhang J, Bao C, Zhang J, Li R, Chen X, Wu S, Wen J, Wei S, Li H, Cai H, Yang X, Zhao Y
Life sciences 2020 May 1;248:117456
Life sciences 2020 May 1;248:117456
A RIG-I-like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination.
Min YQ, Ning YJ, Wang H, Deng F
The Journal of biological chemistry 2020 Jul 10;295(28):9691-9711
The Journal of biological chemistry 2020 Jul 10;295(28):9691-9711
Human Papillomavirus 16 E5 Inhibits Interferon Signaling and Supports Episomal Viral Maintenance.
Scott ML, Woodby BL, Ulicny J, Raikhy G, Orr AW, Songock WK, Bodily JM
Journal of virology 2020 Jan 6;94(2)
Journal of virology 2020 Jan 6;94(2)
Suppression of Stromal Interferon Signaling by Human Papillomavirus 16.
Raikhy G, Woodby BL, Scott ML, Shin G, Myers JE, Scott RS, Bodily JM
Journal of virology 2019 Oct 1;93(19)
Journal of virology 2019 Oct 1;93(19)
Label-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-α Identifies Antiviral Proteins Enriched in Exosomes.
Yao Z, Jia X, Megger DA, Chen J, Liu Y, Li J, Sitek B, Yuan Z
Journal of proteome research 2019 Mar 1;18(3):855-864
Journal of proteome research 2019 Mar 1;18(3):855-864
Alpha/beta interferon receptor deficiency in mice significantly enhances susceptibility of the animals to pseudorabies virus infection.
Wei J, Ma Y, Wang L, Chi X, Yan R, Wang S, Li X, Chen X, Shao W, Chen JL
Veterinary microbiology 2017 May;203:234-244
Veterinary microbiology 2017 May;203:234-244
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
Torres-Odio S, Key J, Hoepken HH, Canet-Pons J, Valek L, Roller B, Walter M, Morales-Gordo B, Meierhofer D, Harter PN, Mittelbronn M, Tegeder I, Gispert S, Auburger G
Journal of neuroinflammation 2017 Aug 2;14(1):154
Journal of neuroinflammation 2017 Aug 2;14(1):154
Herpes Simplex Virus 1 Tegument Protein UL41 Counteracts IFIT3 Antiviral Innate Immunity.
Jiang Z, Su C, Zheng C
Journal of virology 2016 Dec 15;90(24):11056-11061
Journal of virology 2016 Dec 15;90(24):11056-11061
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 23247-1-AP( IFIT1 Antibody) at dilution of 1:600
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- LPS treated RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 23247-1-AP( IFIT1 Antibody) at dilution of 1:600
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- U-937 cells were subjected to SDS PAGE followed by western blot with 23247-1-AP( IFIT1 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IFIT1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IFIT1. This antibody recognizes human antigen. The IFIT1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.