Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN954067 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C) (AA 278-308), (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 278-308, Middle Region
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Inflammatory priming predisposes mice to age-related retinal degeneration.
Characterization of human cone phosphodiesterase-6 ectopically expressed in Xenopus laevis rods.
A homologous genetic basis of the murine cpfl1 mutant and human achromatopsia linked to mutations in the PDE6C gene.
Homozygosity mapping reveals PDE6C mutations in patients with early-onset cone photoreceptor disorders.
Mustafi D, Maeda T, Kohno H, Nadeau JH, Palczewski K
The Journal of clinical investigation 2012 Aug;122(8):2989-3001
The Journal of clinical investigation 2012 Aug;122(8):2989-3001
Characterization of human cone phosphodiesterase-6 ectopically expressed in Xenopus laevis rods.
Muradov H, Boyd KK, Haeri M, Kerov V, Knox BE, Artemyev NO
The Journal of biological chemistry 2009 Nov 20;284(47):32662-9
The Journal of biological chemistry 2009 Nov 20;284(47):32662-9
A homologous genetic basis of the murine cpfl1 mutant and human achromatopsia linked to mutations in the PDE6C gene.
Chang B, Grau T, Dangel S, Hurd R, Jurklies B, Sener EC, Andreasson S, Dollfus H, Baumann B, Bolz S, Artemyev N, Kohl S, Heckenlively J, Wissinger B
Proceedings of the National Academy of Sciences of the United States of America 2009 Nov 17;106(46):19581-6
Proceedings of the National Academy of Sciences of the United States of America 2009 Nov 17;106(46):19581-6
Homozygosity mapping reveals PDE6C mutations in patients with early-onset cone photoreceptor disorders.
Thiadens AA, den Hollander AI, Roosing S, Nabuurs SB, Zekveld-Vroon RC, Collin RW, De Baere E, Koenekoop RK, van Schooneveld MJ, Strom TM, van Lith-Verhoeven JJ, Lotery AJ, van Moll-Ramirez N, Leroy BP, van den Born LI, Hoyng CB, Cremers FP, Klaver CC
American journal of human genetics 2009 Aug;85(2):240-7
American journal of human genetics 2009 Aug;85(2):240-7
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
