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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB4173 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4173, RRID:AB_1579053
- Product name
- PPP6C polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PPP6C.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.
Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade.
Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.
Yang J, Roe SM, Cliff MJ, Williams MA, Ladbury JE, Cohen PT, Barford D
The EMBO journal 2005 Jan 12;24(1):1-10
The EMBO journal 2005 Jan 12;24(1):1-10
Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade.
Zhou G, Golden T, Aragon IV, Honkanen RE
The Journal of biological chemistry 2004 Nov 5;279(45):46595-605
The Journal of biological chemistry 2004 Nov 5;279(45):46595-605
Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.
Huang S, Shu L, Easton J, Harwood FC, Germain GS, Ichijo H, Houghton PJ
The Journal of biological chemistry 2004 Aug 27;279(35):36490-6
The Journal of biological chemistry 2004 Aug 27;279(35):36490-6
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PPP6C polyclonal antibody (Cat # PAB4173) is used in Western blot to detect PPP6C in Thymus tissue lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with PPP6C polyclonal antibody (Cat # PAB4173) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
