BS5788

antibody from Bioworld Technology, Inc
Targeting: MAD2L1BP CMT2, dJ261G23.1, KIAA0110
Provider product page for BS5788

Antibody data

Product number
BS5788 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MAD2L1BP polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 40-85 of Human MAD2L1BP.
Description
MAD2L1BP (MAD2L1 binding protein), also known as CMT2, is a 274 amino acid protein that localizes to the nucleoplasm during early mitosis and to the spindle from metaphase through anaphase. Functioning as a component of the spindle checkpoint (which delays the onset of anaphase until kineotochore attachment is complete), MAD2L1BP is thought to coordinate cell cycle events in late mitosis, possibly binding to MAD2, thereby silencing the spindle checkpoint and allowing mitosis to proceed. MAD2L1BP is expressed as multiple alternative spliced isforms that, upon DNA damage, may be phosphorylated by ATM or ATR. The gene encoding MAD2L1BP maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MAD2L1BP protein structure - BS5788 shown in red.