BS7945

antibody from Bioworld Technology, Inc
Targeting: HMGN2 HMG17
Provider product page for BS7945
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7945 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HMGN2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HMGN2.
Description
The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription. HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates. HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence. Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber. In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development .
Reactivity
Human, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HMGN2 protein structure - BS7945 shown in red.