APR02326G

antibody from Leading Biology

Targeting: MAGEA3 CT1.3, HIP8, HYPD, MAGE3, MGC14613

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR02326G

Provider

Leading Biology

Product name

MAGEA3 Antibody (aa298-314)

Antibody type

Polyclonal

Description

Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.