Tissue expression
Cell line expression
Protein structure
RASSF1
Ras association domain family member 1123F2, NORE2A, RDA32, REH3P21
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
Top validated antibodies |
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Novus Biologicals | NBP2-03644 | 1 references | Monoclonal |
WB
ICC
IHC
FC |
|
OriGene | SM6017 | 1 references | Monoclonal |
WB
EL
ICC
FC |
|
Invitrogen Antibodies | CF502449 | Monoclonal |
WB
ICC
IHC
FC |
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antibodies-online | ABIN4349434 | Monoclonal |
WB
ICC
IHC
FC |
||
LSBio | LS-B10044 | Monoclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider