BS4312

antibody from Bioworld Technology, Inc
Targeting: ERF PE-2, PE2
Provider product page for BS4312
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS4312 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ERF (phospho T526) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human ERF around the phosphorylation site of Threonine 526.
Description
ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the Ets family of transcription factors. The members of the Ets family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets-2 repressor factor) is a ubiquitously expressed Ets-domain protein that exhibits strong transcriptional repressor activity, suppresses Ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by Ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G1 phase.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ERF protein structure - BS4312 shown in red.