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- References [4]
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- Product number
- NB100-59742 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-59742, RRID:AB_2213578
- Product name
- Goat Polyclonal UCP2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references S-adenosyl methionine prevents endothelial dysfunction by inducing heme oxygenase-1 in vascular endothelial cells.
Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats.
Angiotensin receptor blockade recovers hepatic UCP2 expression and aconitase and SDH activities and ameliorates hepatic oxidative damage in insulin resistant rats.
Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action.
Kim SY, Hong SW, Kim MO, Kim HS, Jang JE, Leem J, Park IS, Lee KU, Koh EH
Molecules and cells 2013 Oct;36(4):376-84
Molecules and cells 2013 Oct;36(4):376-84
Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats.
Vázquez-Medina JP, Popovich I, Thorwald MA, Viscarra JA, Rodriguez R, Sonanez-Organis JG, Lam L, Peti-Peterdi J, Nakano D, Nishiyama A, Ortiz RM
American journal of physiology. Heart and circulatory physiology 2013 Aug 15;305(4):H599-607
American journal of physiology. Heart and circulatory physiology 2013 Aug 15;305(4):H599-607
Angiotensin receptor blockade recovers hepatic UCP2 expression and aconitase and SDH activities and ameliorates hepatic oxidative damage in insulin resistant rats.
Montez P, Vázquez-Medina JP, Rodríguez R, Thorwald MA, Viscarra JA, Lam L, Peti-Peterdi J, Nakano D, Nishiyama A, Ortiz RM
Endocrinology 2012 Dec;153(12):5746-59
Endocrinology 2012 Dec;153(12):5746-59
Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action.
De Souza CT, Araújo EP, Stoppiglia LF, Pauli JR, Ropelle E, Rocco SA, Marin RM, Franchini KG, Carvalheira JB, Saad MJ, Boschero AC, Carneiro EM, Velloso LA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Apr;21(4):1153-63
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Apr;21(4):1153-63
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: UCP2 Antibody [NB100-59742] - Staining of rat adipose (A) and mouse spleen (B) lysate (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Detected by chemiluminescence. Approx 37 kDa band observed in rat adipose and 28-30 kDa in mouse spleen lysates (calculated MW of 33.4kDa according to Mouse NP_035801.3 and 33.4kDa according to Rat NP_062227.2).
