CABT-BL3064

antibody from Creative Diagnostics

Targeting: PTPRU FMI, hPTP-J, PCP-2, PTP, PTPRO

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-BL3064

Provider

Creative Diagnostics

Product name

Anti-PTPRU monoclonal antibody, clone 875300

Antibody type

Monoclonal

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

875300

Storage

4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.