SNRNP27

This gene encodes a serine/arginine-rich (SR) protein. SR proteins play important roles in pre-mRNA splicing by facilitating the recognition and selection of splice sites. The encoded protein associates with the 25S U4/U6.U5 tri-snRNP, a major component of the U2-type spiceosome. The expression of this gene may be altered in cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1) retrovirus. A pseudogene of this gene is located on the long arm of chromosome 5. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Description

Small nuclear ribonucleoprotein U4/U6.U5 subunit 27

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

2 (69893956 - 69905575)

Ensembl ID

ENSG00000124380  (ver. 103.38)

Orthologs

Mouse Snrnp27: ENSMUSG00000001158

UniProt

Q8WVK2

neXtProt

NX_Q8WVK2

Human splice variants
Mouse splice variants

Protein structure