BS7931

antibody from Bioworld Technology, Inc
Targeting: EMSY C11orf30
Provider product page for BS7931
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7931 - Provider product page
Provider
Bioworld Technology, Inc
Product name
C11orf30 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human C11orf30.
Description
EMSY interacts with BRCA2 and plays a role in chromatin remodeling. This interaction has been confirmed in HeLa cells. Overexpression of EMSY strongly correlates with amplification in sporadic breast cancer and higher grade ovarian cancer. The EMSY gene is amplified in 18% of breast cancer cell lines. EMSY amplification is highly correlated with DNA amplification in both cell lines and primary tumors. This amplification is a general sign of poor prognosis and shortened disease-free survival time. EMSY from a wide variety of species has a conserved 80 amino acid sequence at the N-terminus. In irradiated MEFs (mouse embryonic fibroblasts), EMSY was found to migrate to damaged DNA.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EMSY protein structure - BS7931 shown in red.