AF3357

antibody from R&D Systems

Targeting: NDUFC2 B14.5b, HLC-1

Western blot (Data presented on provider website)

Antibody Data

Product number

AF3357

Provider

R&D Systems

Product name

Mouse Matrilin-3 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects mouse Matrilin-3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human Matrilin-3 is observed and 5% cross-reactivity with recombinant mouse (rm) Matrilin-2 and rmMatrilin-4 is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Unconjugated

Antigen sequence

AAH71224


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease.

Piróg KA, Dennis EP, Hartley CL, Jackson RM, Soul J, Schwartz JM, Bateman JF, Boot-Handford RP, Briggs MD
PLoS genetics 2019 Jul;15(7):e1008215

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An inducible cartilage oligomeric matrix protein mouse model recapitulates human pseudoachondroplasia phenotype.

Posey KL, Veerisetty AC, Liu P, Wang HR, Poindexter BJ, Bick R, Alcorn JL, Hecht JT
The American journal of pathology 2009 Oct;175(4):1555-63

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Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.

Posey KL, Hankenson K, Veerisetty AC, Bornstein P, Lawler J, Hecht JT
The American journal of pathology 2008 Jun;172(6):1664-74