Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 26416-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- cGAS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated cGAS antibody (Cat. #26416-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Activation of the cGAS-STING signaling pathway in adenomyosis patients.
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Small molecule inhibition of cyclic GMP-AMP synthase ameliorates sepsis-induced cardiac dysfunction in mice.
BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses.
Airway Epithelial cGAS Is Critical for Induction of Experimental Allergic Airway Inflammation.
Melatonin inhibits cytosolic mitochondrial DNA-induced neuroinflammatory signaling in accelerated aging and neurodegeneration.
mTOR Dysregulation by Vaccinia Virus F17 Controls Multiple Processes with Varying Roles in Infection.
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.
Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit.
HLA-DMB restricts human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG7 acetylation.
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.
Restriction of Human Cytomegalovirus Replication by ISG15, a Host Effector Regulated by cGAS-STING Double-Stranded-DNA Sensing.
Lin Y, Wang L, Ye M, Yu KN, Sun X, Xue M, Deng X
Immunity, inflammation and disease 2021 Sep;9(3):932-942
Immunity, inflammation and disease 2021 Sep;9(3):932-942
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Han F, Guo H, Wang L, Zhang Y, Sun L, Dai C, Wu X
Experimental eye research 2021 Jan;202:108366
Experimental eye research 2021 Jan;202:108366
Small molecule inhibition of cyclic GMP-AMP synthase ameliorates sepsis-induced cardiac dysfunction in mice.
Xu Q, Xiong H, Zhu W, Liu Y, Du Y
Life sciences 2020 Nov 1;260:118315
Life sciences 2020 Nov 1;260:118315
BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses.
Wang J, Li GL, Ming SL, Wang CF, Shi LJ, Su BQ, Wu HT, Zeng L, Han YQ, Liu ZH, Jiang DW, Du YK, Li XD, Zhang GP, Yang GY, Chu BB
PLoS pathogens 2020 Mar;16(3):e1008429
PLoS pathogens 2020 Mar;16(3):e1008429
Airway Epithelial cGAS Is Critical for Induction of Experimental Allergic Airway Inflammation.
Han Y, Chen L, Liu H, Jin Z, Wu Y, Wu Y, Li W, Ying S, Chen Z, Shen H, Yan F
Journal of immunology (Baltimore, Md. : 1950) 2020 Mar 15;204(6):1437-1447
Journal of immunology (Baltimore, Md. : 1950) 2020 Mar 15;204(6):1437-1447
Melatonin inhibits cytosolic mitochondrial DNA-induced neuroinflammatory signaling in accelerated aging and neurodegeneration.
Jauhari A, Baranov SV, Suofu Y, Kim J, Singh T, Yablonska S, Li F, Wang X, Oberly P, Minnigh MB, Poloyac SM, Carlisle DL, Friedlander RM
The Journal of clinical investigation 2020 Jun 1;130(6):3124-3136
The Journal of clinical investigation 2020 Jun 1;130(6):3124-3136
mTOR Dysregulation by Vaccinia Virus F17 Controls Multiple Processes with Varying Roles in Infection.
Meade N, King M, Munger J, Walsh D
Journal of virology 2019 Aug 1;93(15)
Journal of virology 2019 Aug 1;93(15)
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
Yang B, Song D, Liu Y, Cui Y, Lu G, Di W, Xing H, Ma L, Guo Z, Guan Y, Wang H, Wang J
FEBS letters 2018 May;592(10):1693-1704
FEBS letters 2018 May;592(10):1693-1704
Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.
Lum KK, Song B, Federspiel JD, Diner BA, Howard T, Cristea IM
Cell systems 2018 Dec 26;7(6):627-642.e6
Cell systems 2018 Dec 26;7(6):627-642.e6
Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit.
Meade N, Furey C, Li H, Verma R, Chai Q, Rollins MG, DiGiuseppe S, Naghavi MH, Walsh D
Cell 2018 Aug 23;174(5):1143-1157.e17
Cell 2018 Aug 23;174(5):1143-1157.e17
HLA-DMB restricts human T-cell leukemia virus type-1 (HTLV-1) protein expression via regulation of ATG7 acetylation.
Wang J, Song D, Liu Y, Lu G, Yang S, Liu L, Gao Z, Ma L, Guo Z, Zhang C, Wang H, Yang B
Scientific reports 2017 Oct 31;7(1):14416
Scientific reports 2017 Oct 31;7(1):14416
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.
Wang J, Kang L, Song D, Liu L, Yang S, Ma L, Guo Z, Ding H, Wang H, Yang B
Journal of immunology (Baltimore, Md. : 1950) 2017 Oct 1;199(7):2475-2482
Journal of immunology (Baltimore, Md. : 1950) 2017 Oct 1;199(7):2475-2482
Restriction of Human Cytomegalovirus Replication by ISG15, a Host Effector Regulated by cGAS-STING Double-Stranded-DNA Sensing.
Bianco C, Mohr I
Journal of virology 2017 May 1;91(9)
Journal of virology 2017 May 1;91(9)
No comments: Submit comment
No validations: Submit validation data