Ab133998

antibody from Aladdin Scientific Corporation

Targeting: VDAC1 MGC111064, PORIN

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab133998

Provider

Aladdin Scientific Corporation

Product name

VDAC1/Porin Antibody

Antibody type

Polyclonal

Description

Rabbit anti Human VDAC1/Porin Antibody, Polyclonal antibody, could be used for WB, IHC and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100Protein Function:Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 3-16


Vial size

100μl,10μl,1ml,50μl

Concentration

0,1 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.