11-6003

antibody from ABEOMICS Inc.
Targeting: CUEDC2 C10orf66, MGC2491
Provider product page for 11-6003

Antibody data

Product number
11-6003 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-CUEDC2 Antibody
Antibody type
Polyclonal
Description
CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant CUEDC2
protein (amino acids 100-280) was
used as the immunogen for this anti
body.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
CUEDC2 protein structure - 11-6003 shown in red.