Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11-6003-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-CUEDC2 Antibody
- Antibody type
- Polyclonal
- Description
- CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant CUEDC2
protein (amino acids 100-280) was
used as the immunogen for this anti
body.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
No comments: Submit comment
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of CUEDC2. Anti-CUEDC2 antibody (11-6003) was used at 2 µg/ml on 1) Y79, 2) Kidney lysates.