Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- H00083987-B01P - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#H00083987-B01P, RRID:AB_10714349
- Product name
- CCDC8 purified MaxPab mouse polyclonal antibody (B01P)
- Antibody type
- Polyclonal
- Description
- Mouse polyclonal antibody raised against a full-length human CCDC8 protein.
- Antigen sequence
MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEA
EFRERLTQFLEEEGRTLEDVARIMEKSTPHPPQPP
KKPKEPRVRRRVQQMVTPPPRLVVGTYDSSNASDS
EFSDFETSRDKSRQGPRRGKKVRKMPVSYLGSKFL
GSDLESEDDEELVEAFLRRQEKQPSAPPARRRVNL
PVPMFEDNLGPQLSKADRWREYVSQVSWGKLKRRV
KGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSP
GDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKE
QTAPTGQGADIEADQGGEAADSQREEAIADQREGA
AGNQRAGAPADQGAEAADNQREEAADNQRAGAPAE
EGAEAADNQREEAADNQRAEAPADQRSQGTDNHRE
EAADNQRAEAPADQGSEVTDNQREEAVHDQRERAP
AVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAE
VSAAQGTTGTAPGARARKQVKTVRFQTPGRFSWFC
KRRRAFWHTPRLPTLPKRVPRAGEARNLRVLRAEA
RAEAEQGEQEDQL- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Submitted references Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth.
Hanson D, Murray PG, O'Sullivan J, Urquhart J, Daly S, Bhaskar SS, Biesecker LG, Skae M, Smith C, Cole T, Kirk J, Chandler K, Kingston H, Donnai D, Clayton PE, Black GC
American journal of human genetics 2011 Jul 15;89(1):148-53
American journal of human genetics 2011 Jul 15;89(1):148-53
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western Blot analysis of CCDC8 expression in transfected 293T cell line (H00083987-T01) by CCDC8 MaxPab polyclonal antibody.Lane 1: CCDC8 transfected lysate(59.40 KDa).Lane 2: Non-transfected lysate.
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- CCDC8 MaxPab polyclonal antibody. Western Blot analysis of CCDC8 expression in rat brain.