FNab00576

antibody from FineTest Biotech

Targeting: ARL3 ARFL3

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Immunocytochemistry

Immunohistochemistry

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Validation data

Product number: FNab00576 - Provider product page
Provider: FineTest Biotech
Product name: ARL3 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: ADP-ribosylation factor-like 3
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ARL3 protein structure - FNab00576 shown in red.