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CYP17A1
Cytochrome P450 family 17 subfamily A member 1CPT7, CYP17, P450C17, S17AH
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  14447-1-AP |
19 references | Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | BSM-54306R |
Monoclonal |
WB
ICC
IHC
FC
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| Cusabio Biotech Co., Ltd | CSB-PA006392EA01HU |
1 references | Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NB100-2842 |
3 references | Polyclonal |
WB
EL
IHC
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| OriGene | TA503442 |
1 references | Monoclonal |
WB
IHC
FC
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