APG00283G

antibody from Leading Biology

Targeting: RNF34 FLJ21786, RIF, RIFF

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APG00283G

Provider

Leading Biology

Product name

Goat Anti-RNF34 / RFI (N Terminus) Antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Reactivity

Human

Host

Goat

Isotype

IgG

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.