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Protein structure
PTPRG
Protein tyrosine phosphatase receptor type GPTPG, RPTPG
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-15524 |
2 references | Polyclonal |
WB
OA
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| Novus Biologicals | NBP1-02517 |
1 references | Polyclonal |
EL
IHC
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| antibodies-online | ABIN954380 |
4 references | Polyclonal |
WB
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| R&D Systems | MAB4608 |
2 references | Monoclonal |
WB
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| Abnova Corporation | PAB4092 |
3 references | Polyclonal |
WB
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