Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 16814-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16814-1-AP, RRID:AB_2117572
- Product name
- HIP1R antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HIP1R antibody (Cat. #16814-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
A peptidic inhibitor for PD-1 palmitoylation targets its expression and functions.
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy.
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
HIP1R Expression and Its Association with PD-1 Pathway Blockade Response in Refractory Advanced NonSmall Cell Lung Cancer: A Gene Set Enrichment Analysis.
HIP1R targets PD-L1 to lysosomal degradation to alter T cell-mediated cytotoxicity.
Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours.
Proteomic analysis identifies NPTX1 and HIP1R as potential targets of histone deacetylase-3-mediated neurodegeneration.
Koikawa K, Kibe S, Suizu F, Sekino N, Kim N, Manz TD, Pinch BJ, Akshinthala D, Verma A, Gaglia G, Nezu Y, Ke S, Qiu C, Ohuchida K, Oda Y, Lee TH, Wegiel B, Clohessy JG, London N, Santagata S, Wulf GM, Hidalgo M, Muthuswamy SK, Nakamura M, Gray NS, Zhou XZ, Lu KP
Cell 2021 Sep 2;184(18):4753-4771.e27
Cell 2021 Sep 2;184(18):4753-4771.e27
A peptidic inhibitor for PD-1 palmitoylation targets its expression and functions.
Yao H, Li C, He F, Song T, Brosseau JP, Wang H, Lu H, Fang C, Shi H, Lan J, Fang JY, Xu J
RSC chemical biology 2021 Feb 1;2(1):192-205
RSC chemical biology 2021 Feb 1;2(1):192-205
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy.
Gao Y, Nihira NT, Bu X, Chu C, Zhang J, Kolodziejczyk A, Fan Y, Chan NT, Ma L, Liu J, Wang D, Dai X, Liu H, Ono M, Nakanishi A, Inuzuka H, North BJ, Huang YH, Sharma S, Geng Y, Xu W, Liu XS, Li L, Miki Y, Sicinski P, Freeman GJ, Wei W
Nature cell biology 2020 Sep;22(9):1064-1075
Nature cell biology 2020 Sep;22(9):1064-1075
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
Seervai RNH, Jangid RK, Karki M, Tripathi DN, Jung SY, Kearns SE, Verhey KJ, Cianfrocco MA, Millis BA, Tyska MJ, Mason FM, Rathmell WK, Park IY, Dere R, Walker CL
Science advances 2020 Oct;6(40)
Science advances 2020 Oct;6(40)
HIP1R Expression and Its Association with PD-1 Pathway Blockade Response in Refractory Advanced NonSmall Cell Lung Cancer: A Gene Set Enrichment Analysis.
Koh YW, Han JH, Haam S, Lee HW
Journal of clinical medicine 2020 May 11;9(5)
Journal of clinical medicine 2020 May 11;9(5)
HIP1R targets PD-L1 to lysosomal degradation to alter T cell-mediated cytotoxicity.
Wang H, Yao H, Li C, Shi H, Lan J, Li Z, Zhang Y, Liang L, Fang JY, Xu J
Nature chemical biology 2019 Jan;15(1):42-50
Nature chemical biology 2019 Jan;15(1):42-50
Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours.
Yao H, Lan J, Li C, Shi H, Brosseau JP, Wang H, Lu H, Fang C, Zhang Y, Liang L, Zhou X, Wang C, Xue Y, Cui Y, Xu J
Nature biomedical engineering 2019 Apr;3(4):306-317
Nature biomedical engineering 2019 Apr;3(4):306-317
Proteomic analysis identifies NPTX1 and HIP1R as potential targets of histone deacetylase-3-mediated neurodegeneration.
Qu Z, D'Mello SR
Experimental biology and medicine (Maywood, N.J.) 2018 Apr;243(7):627-638
Experimental biology and medicine (Maywood, N.J.) 2018 Apr;243(7):627-638
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 16814-1-AP(HIP1R antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HIP1R antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HIP1R. This antibody recognizes human,mouse,rat antigen. The HIP1R antibody has been validated for the following applications: ELISA, WB, IHC analysis.