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Protein structure
UNG
Uracil DNA glycosylaseDGU, HIGM4, UDG, UNG1, UNG2
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]
Top validated antibodies |
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| LSBio |  LS-B10107 |
Polyclonal |
WB
EL
ICC
IHC
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| Proteintech Group | 12394-1-AP |
1 references | Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NB600-1031 |
4 references | Polyclonal |
WB
ICC
IHC
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| OriGene | TA503563 |
2 references | Monoclonal |
WB
ICC
IHC
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| Boster Biological Technology | A01672-2 |
Polyclonal |
WB
EL
ICC
IHC
FC
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