BS2254

antibody from Bioworld Technology, Inc

Targeting: ADRA2A ADRA2, ADRA2R, ADRAR

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: BS2254 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS2254, RRID:AB_1663501
Product name: AR Ï«2A (R361) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 331-380 of Human AR-Ï«2A.
Description: This study investigates the involvement of Ï«2-adrenergic receptors (AR) in mouse brain induced by a low dose of methamphetamine (METH, 2 mg/kg). Immunohistochemical studies show that Ï«2A-AR increased in the dentate gyrus area of the hippocampus 24 h after five repeated administrations of METH. The hippocampal Ï«2A-AR proteins rose 3.2-fold when compared to the saline-administered mice. The other adrenergic receptor, Ï«1D-AR, were not changed by the treatment. Moreover, Ï«o-subunits of GTP-binding proteins (GÏ«o), one of the downstream molecules of Ï«2A-AR, was also increased by the treatment. These suggest that the repeated administration of low-doses of METH causes quantitative changes of the signaling of Ï«2A-AR in the mouse hippocampus.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ADRA2A protein structure - BS2254 shown in red.