BS60744

antibody from Bioworld Technology, Inc
Targeting: RASIP1 FLJ20401, RAIN
Provider product page for BS60744

Antibody data

Product number
BS60744 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RASIP1 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human RASIP1
Description
RAIN, also known as RASIP1 (Ras-interacting protein 1), is a 963 amino acid protein that contains one dilute domain and one Ras-associating domain. The RAIN protein is highly expressed in heart and detected at lower levels in placenta and pancreas. RAIN interacts with H-Ras, Rap 1A, Rap 2, R-Ras, Raf-1 and TC 21, as well as with Ras family members that have been activated by GTP binding. RAIN interacts with Ras in a GTP-dependent manner in vitro and in vivo, requiring an intact Ras core effector-binding domain for this interaction, and thus fits the definition of a Ras effector. Unlike other Ras effectors, RAIN localizes to the perinuclear, juxta-Golgi vesicles in intact cells and is recruited to the Golgi by activated Ras. Containing twelve exons, the RAIN gene is conserved in dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 19q13.33.
Reactivity
Human, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RASIP1 protein structure - BS60744 shown in red.