BS6108

antibody from Bioworld Technology, Inc
Targeting: SNAI2 SLUG, SLUGH, SLUGH1, SNAIL2
Provider product page for BS6108
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6108 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SNAI2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SNAI2.
Description
SNAI 1 and SLUG are expressed in placenta and in adult heart, liver, and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. SLUG is implicated in the generation and migration of neural crest cells in human embryos and also contributes to limb bud development. In addition, SLUG also constitutes a cellular anti-apoptotic transcription factor that effectively prevents apoptosis in murine pro-B cells deprived of IL-3. The SNAIL-related gene from murine skeletal muscle cells, Smuc, is highly expressed in skeletal muscle and thymus and can, likewise, repress gene transcription.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SNAI2 protein structure - BS6108 shown in red.